Stem Cell Basics

 

 

Fat as Stem Cell Source

 


ASCs (Adipose-derived Stem Cells)

 

 

Adipose tissue is a very rich source of stem cells, and contains 500 times more MSCs

per gram than bone marrow [Fraser 2006].

 

Furthermore, lipoaspirate as collected in the Cryo-Lip procedure consists of a heterogeneous cell population including pericytes, endothelial cells, adipocyte progenitors and fibroblasts. [Gimble 2007].

 
ASCS have been shown to be good candidates for clinical applications because of their


        1   capability to proliferate and produce large cell numbers   
  2 robustness, relatively easy to culture and expand  
  3 multipotent differentiation characteristics  
    - ASCs have been differentiated into these lineages:  [Bobis 2006, Fraser 2006, Gimble 2003, Garcia-Castro 2008]

                         Adipocyte  
    Chondrocyte  
    Myocyte  
    Endothelial  
    Cardiomyocyte  
    Osteocyte  
    Neuronal-like  
    Hepatocyte  
   

Pancreatic endocrine

(insulin, glucagon)

 


 
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